Rent, Lease, or Buy BioGravity™ Platform

What Is an Explor Space BioGravity™ RPM Machine?

The Random Positioning Machine (RPM) was developed by Dr. Joshua Chou at University Technology Sydney to do bioengineering experiments in zero or reduced gravity here on Earth without going into space.

THE GRAVITATIONAL UNLOADING DEVICE FOR YOUR LAB:

the most cost-effective and simple way to perform microgravity experiments – in your own contract lab.

Ready to Launch in 10 minutes! The Explor Microgravity RPM uses random positioning to simulate gravitational unloading in cells.

The RPM rotates any enclosed experiment ‘randomly’ to minimize the influence of Earth’s gravity, thereby simulating what would be experienced in space. The BioGravity successfully simulate zero gravity, typically referred to as microgravity or in biology, known as gravitational unloading. The newer RPM can additionally simulate partial gravity, which is between 0g and 1g. Uniquely the BioGravity Platform can approach 10-3.

A look at lung cells after gravitational unloading before and after simulated microgravity using the Explor RPM

A random positioning machine, or RPM, rotates biological samples along two or more independent axes to change their orientation in space in complex ways and so eliminate the effect of gravity.

MORE THAN 5 BENEFITS OF THE BIOGRAVITY RANDOM POSITIONING MACHINE:

  • Low Cost- One-time fee enables endless experimenting and predictable costs
  • Faster Iterations- Desktop RPM is always there in the lab
  • Endless Time of Simulated Microgravity-Unlike suborbital spacecrafts (5-10 min), parabolic flights (20 s) and drop towers (9 s) unload gravity on your timetable for as long as you want.
  • Prepare for Flight | Reduce Variables- Duplication of expected results are far more guaranteed when you shakeout your biological experiments on the ground. Control for the effects of launch, radiation exposure, descent, and ground transport with a BioGravity platform in your own lab.
  • No Schedule Bumps, Military Delays or NASA Manifests-Cut through bureaucracy. It’s your experiment, deploy when you want on your own platform,
  • Push for Progressive Grants-Nothing sets up success like prior success. Get an early read and practical results without venturing to the heavens.

BIOGRAVITY™ PLATFORM fits inside most standard incubators (not included)

  •  96 Well Plate or 250mL BioReactor Platform is standard.
  • Platform rated to 400 grams.
  • Non-magnetic.
  • Radiation tested.
  • Rated to over 3,000 hours continuous use.
  • Calibrated g performance to 10-3.
  • Software included.
  • Free shipping within 48 hours. Overnight replacement guarantee.
  • Machined in Japan. Assembled and Landed in USA.
  • No tariff, import duties or VAT taxes.
  • One hour virtual training included with Dr. James Secrest.
  • Up to one hour experiment consultation (virtual) with Dr Joshua Chou or UTS team member.
  • Device will be calibrated using a standard accelerometer application on iPhone.
  •  The BioGravity  Platform is the exclusive licensee in North America for sales and service of the Explor Space Simulated Microgravity RPM by biomedical engineer Dr. Joshua Chou at University Technology Sydney. 
  • Bulk discount on 10 or more serial-linked platforms. 
  • Larger capacity designs available including our MERLIN pre-flight microgravity platform.

Developed in conjunction with Dr. Joshua Chou and his team at the University Technology Sydney, BioGravity LLC holds the exclusive North American Distribution Rights to the Explor Space BioGravity devices, providing sales, consulting, distribution, set up and analysis consulting.

BioGravity is a Clinical Research Organization lead by 25 year researcher  Dr. James Secrest . We are a premier end-to-end verification source for validating both demonstration and clinical trials. Our focus is on the practical assessment and deployment of microgravity discovery paths through simple and practical innovations.

Located at the Innovation Center at the University of Western Michigan Medical School, BioGravity LLC offers space biology development for Biotech, Agriculture, Veterinary and Pharma R&D. For the Michigan Space Station, we offer a novel form of stem cell and biologic discovery paths using simulated, computational and on-station clinical research in microgravity.

For other microgravity labs and NASA spaceflight payload integration specialists such as Rhodium Scientific, we provide a platform for pre-flight and theorem testing using baseline or bench cell comparisons, and end-to-end verification as needed for trials.

Our focus is on the practical assessment and deployment of microgravity discovery paths through simple and practical innovations.

The BioGravity Platform is where the actual random positioning and gravitational unloading takes place. It can host up to 15 variable sample vessels or a 96 well plate on its aluminum platform.

Besides microgravity, it is possible to simulate the gravity of International Space Station, Moon and Mars with the included software, GravityDial. This software controls variable pitch, roll and intensity algorithms. (Some extreme intensities void the purchase warranty and require signoff before the software is unlocked)

This module is designed to be used inside an incubator. The BioGravity Platform is controlled via USB interface screen located on the side of the unit and connects to most standard laptops (not included).

BIOGRAVITY USES:

Our goal is to make the Explor RPM a central part of true microgravity discovery through on-bench and simultaneous uG verification. Primarily, we provide lasting collaboration in the fields of:

  1. Microgravity Validation and Pre-Flight Experiment Diagnostics in Macrophage
  2. Development of Stem Cell Production and Manufacturing
  3. Continuation of Cancer Tumor studies
  4. Exosome and other Secretive Cell Signaling
  5. Novel drug discovery and protein crystallization projects including compound re-characterization
  6. Tissue and Bone Therapy Screening
  7. Patent Development and Filings

Additional Custom and Co-Development of Accessories: We offer mutual or simul-track development of:

  1. Industrial-sized RPMs for mounting incubator on device such as Merlin
  2. Inline Actuation Systems using belt-driven magnetic array
  3. Inline High-Speed Cell Imaging
  4. Temperature and Humidity Sensors
  5. Non-Destructive Inline Flow Cytometry
  6. Cloud-based machine learning data sharing among Explor Leasees
  7. Project management integrations including ASF Scientific Solutions and Luminare Molecular
  8. BioGravity™ is the only simulated microgravity RPM company in the United States that combines 3D bioprinting technologies (CELLINK) to pioneer and disrupt 3D cell culture and biomimetic biological microenvironments.
  9. Cellink is a leading innovator of bioprinters, bioinks and technologies at the forefront of making on-demand bioprinted human organs and tissues a future reality. When combined with simulated microgravity at the Michigan Space Station, the best-in-class bioprinters not only speed innovations by academics and R&D labs but also make critical breakthroughs—from 3D cell culturing to tissue engineering to drug development– a brilliant reality.

RENT PURCHASE OR COMMISSION THE BIOGRAVITY MICROGRAVITY EXPERIMENT PLATFORM

RENT A COMMERCIAL-GRADE BIOGRAVITY™ PLATFORM FOR YOUR CLASSROOM OR LAB — FOR ABOUT $1100 MONTH.

PURCHASE A BIOGRAVITY™ PLATFORM with a $10,000 discount for academia or non-profit.

COMMISSION A BIOGRAVITY™ EXPERIMENT WITH CLINICAL OR END-TO-END VERIFICATION FROM $15,000 USD Conducted at the MichiganSpaceStation.com integrated with the Western Michigan University Homer Stryker M.D. School of Medicine Innovation Center.

BIOGRAVITY™ PLATFORM fits inside most standard cell culture incubators. Samples in 96 Well Plates or 250mL BioReactor Platforms are standard. Platform rated to 400 grams of total sample load. Larger capacity designs available including our MERLIN pre-flight microgravity platform. Radiation tested. Rated to over 3,000 hours continuous use. Calibrated g performance to 10-3. Software included. Free shipping within 48 hours. Overnight replacement guarantee. Machined in Japan. Assembled and landed in USA. No tariff, import duties or VAT taxes. 1 Protein Synthesis/Fold Experiment Included. Training included. The BioGravity Platform is the exclusive licensee in North America for sales and service of the EXPLOR Space Simulated Microgravity RPM by biomedical engineer Dr. Joshua Chou at University Technology Sydney. Bulk discount on 10 or more serial-linked platforms. Rental, purchase or commission credit for simulated microgravity experiments applied toward later experiment flight on the International Space Station (ISS) when booked through BioGravity, LLC flight partners and integration specialists.

Frank Pournelle Chief Commercial Officer BioGravity LLC Microgravity & Cell Division NOVEL LAB + PRE-CLINIC DISCOVERY 800-334-4500 frank@biotech-net.com

Papers on Simulated Microgravity

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