Advanced MicroGravity R&D to Power the Space Race…from BioGravityLLC

RPM

  • TOP 5 REASON TO CONSIDER THE BIOGRAVITY RPM PLATFORM FOR IN-LAB SIMULATED MICROGRAVITY

Low Cost– One-time fee enables endless experimenting and predictable costs

Faster Iterations– Desktop RPM is always there in the lab

Endless Time of Simulated Microgravity-Unlike suborbital spacecrafts (5-10 min), parabolic flights (20 s) and drop towers (9 s) unload gravity on your timetable for as long as you want.

Prepare for Flight | Reduce Variables– Duplication of expected results are far more guaranteed when you shakeout your biological experiments on the ground. Control for the effects of launch, radiation exposure, descent, and ground transport with a BioGravity platform in your own lab.

No Schedule Bumps, Military Delays or NASA Manifests-Cut through bureaucracy. It’s your experiment, deploy when you want on your own platform,

Push for Progressive Grants-Nothing sets up success like prior success. Get an early read and practical results without venturing to the heavens.

The Michigan Space Station Features the Advanced R&D Capabilities of the Explor Space BioGravity Platform
…the world’s best desktop random positioning machine (RPM)

WHAT TYPES OF RESEARCH CAN YOU DO IN YOUR LAB WITH THE EXPLOR SPACE BIOGRAVITY PLATFORM?

FUNCTION | EXPERIMENTSIMULATEDSPACEFLIGHT
GRAVITATIONAL UNLOADINGYESYES
LOW EARTH ORBITYESYES
MOONYESYES
MARSYESNO
Macrophage DifferentiationYESYES
Decrease Macrophage QuantityYESYES
Decrease Functional PolarizationYESYES
Metabolic ReprogrammingYESYES
Alter Gene Expression ProfilesYESYES
RAS/ERK/NFκB as a major microgravity-regulated pathwayYESYES
Modulation of CytokinesYESYES
Motility In Microbial BehaviorYESYES
ChemotaxisYESYES
Nutrient AssimilationYESYES
Tissue Localization and InvasionYESYES
PathogenicityYESYES
Biofilm FormationYESYES
Prediction of Microbial Changes during SpaceflightYESNO
Low Fluid Shear ConditionsYESYES
Shear Stress ModulationYESYES
Ground-Based Bio-ReactorsYESNO
Replicate WeightlessnessYESYES
Incompressable Fluid EnvironmentYESYES
Fladgellar AssemblyYESYES
Extracellular Vesicles
RADIATION SHEILDINGYESNO
GAMMA RAY SHIELDINGYESNO
SETTLINGYESYES
BOUYANT CONVECTIONYESYES
SPHERICAL AGGLOMORATIONYESYES
CHRYSTALIZATION RESOLUTIONYESYES
ENZYME PURIFICATIONYESYES
Liquefaction or Hydrolysis YESYES
Epidermal Growth FactorsYESYES
Inflamatory ResponseYESYES
Marangoni ConvectionYESYES
Cell Surface InteractionsYESYES
Melanin UV ExperimentsYESYES
3D Structure YESYES
Difraction MicroscopyYESYES
Form a String of Amino AcidsYESYES
Acoustic Reshaping of BubblesYESYES
STEM CELLS
Triggers Epithelial Mesenchymal Transition in Human KeratinocytesYESYES
Bone FormationYESYES
Reduction of Hair FormationYESYES
Lower calcium and potassium currentsYESYES
Organism Cyrcadium Rhythm in MicrogravityYESYES
regeneration in µg on PlatyhelminthesYESYES
cellular and physiological processes in XenopusYESYES
Gravity Deprivation in DrosophilaYESYES
PLANTS
Altering cell membrane integrityYESYES
Accumulation of hazardous substances YESYES
Affectation of Cell Nucleus StructuresYESYES
frequency of mininucleolus YESYES
malondialdehyde (MDA) contentYESYES
superoxide contentYESYES
Changes in cell cycle, cell wall and gene expressionYESYES
bioregenerative life support systemsYESYES
Transcriptomics (e.g. total RNA extraction, RT-PCR and gene array)YESNO
Proteomics (e.g. mass spectrometry)YESNO
Cell viability assay (e.g. trypan blue assay)YESYES
Cell cycle assay (e.g. propidium iodide staining of cellular DNA content)YESYES
Apoptosis (e.g. annexin V – FITC detection)YESNO
Quantitative protein detection (e.g. Western Blot of protein(s) of interest)YESNO
Quantitative protein detection (e.g. immunocytochemistry)YESNO
Transcriptional Level Alterations (e.g. qRT-PCR)YESYES
Post-Transcriptional Level Alterations(e.g. proteomics, cellular markers)YESYES
Cancer-Relevant Cellular Processes
Cell CycleYESYES
ProliferationYESYES
ApoptosisYESYES
Cellular morphology (cytoskeleton)YESYES
Adhesion (extra-cellular matrix)YESYES
MigrationYESYES
Two-dimensional monolayerYESYES
Three-dimensional aggregates (Spheroids)YESYES
Spheroid formation in metastasisYESYES
Cell Matrix and Pathway Growth 
Signalling PathwaysYESYES
Extracellular MatrixYESYES
Focal AdhesionYESYES
Stem Cell & Regenerative Medicines
OsteoblastYESYES
TissueYESYES
CartilageYESYES
Biological MineralizationYESYES
Microbiology
Pro- and EukaryotesYESYES
Pathogens YESYES
Pseudomonas Aeruginosa YESYES
Candida Albicans YESYES
Waste Recylcing
Rhodospirillum RubrumYESYES
Organism ModelingYESYES
 S. Cerevisiae YESYES
Paramecium YESYES
Quorum SensingYESYES
Photosynthetic SystemsYESYES
 Gene Expression YESYES
Production of PigmentsYESYES